http://pucir.inflibnet.ac.in:8080/jspui/handle/123456789/888 Fri, 31 Oct 2025 23:28:53 GMT 2025-10-31T23:28:53Z http://pucir.inflibnet.ac.in:8080/jspui/handle/123456789/913 Title: An insight into black cutworm (Agrotis ipsilon): A glimpse on globally important crop pest Authors: Lalthanzara, H Abstract: Many agricultural pests create problems for farmers leading to production loss. Since agriculture plays an important role in the economy of a nation, controlling and management of such pests is of great importance. Cutworms are notorious agricultural pests infesting a wide variety of crops leading to production loss. Cutworms are distributed worldwide and many species of cutworms have also been reported feeding on all kinds of crops. Agrotis ipsilon is one of the most common cutworm species prevailing in different continents. Understanding the biology and management of these pests will be of great use for farmers. In this article, brief information on cutworms; specifically A. ipsilon species is highlighted. A brief description of host, migration, control and management of A. ipsilon are also highlighted. Mon, 15 Feb 2021 00:00:00 GMT http://pucir.inflibnet.ac.in:8080/jspui/handle/123456789/913 2021-02-15T00:00:00Z http://pucir.inflibnet.ac.in:8080/jspui/handle/123456789/911 Title: THE OUTBREAK OF COVID-19 IN MIZORAM, INDIA Authors: Lalthanzara, H Abstract: For a better understanding, this book represents the incidence of COVID-19 in Mizoram as three different outbreaks. The first outbreak started from the 2nd week of June and lasted till about the 1st week of July. The second outbreak started from the 2nd week of July and lasted till about the 3rd week of October. The third outbreak started from the 4th week of October and as of 26th November 2020, it is still an on-going outbreak with a trend in declining of active cases. The basis of classification into different outbreaks is purely based on the viewpoint of the authors. Also, each outbreak should not be considered as a wave of COVID-19. Thus, the first outbreak of COVID-19 does not mean that it is the first wave of COVID-19 and so on. Tue, 01 Dec 2020 00:00:00 GMT http://pucir.inflibnet.ac.in:8080/jspui/handle/123456789/911 2020-12-01T00:00:00Z http://pucir.inflibnet.ac.in:8080/jspui/handle/123456789/909 Title: Computational guided identification of potential leads from Acacia pennata (L.) Willd. as inhibitors for cellular entry and viral replication of SARS‑CoV‑2 Authors: Lalthanzara, H Abstract: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) started in 2019 and is still an on-going pandemic. SARS-CoV-2 uses a human protease called furin to aid in cellular entry and its main protease ( Mpro) to achieve viral replication. By targeting these proteins, scientists are trying to identify phytoconstituents of medicinal plants as potential therapeutics for COVID-19. Therefore, our study was aimed to identify promising leads as potential inhibitors of SARS-CoV-2 Mpro and furin using the phytocompounds reported to be isolated from Acacia pennata (L.) Willd. Results: A total of 29 phytocompounds were reported to be isolated from A. pennata. Molecular docking simulation studies revealed 9 phytocompounds as having the top 5 binding affinities towards SARS-CoV-2 Mpro and furin. Among these phytocompounds, quercetin-3-O-α-L-rhamnopyranoside (C_18), kaempferol 3-O-α-Lrhamnopyranosyl-( 1 → 4)-β-D-glucopyranoside (C_4), and isovitexin (C_5) have the highest drug score. However, C_18 and C_4 were not selected for further studies due to bioavailability issues and low synthetic accessibility. Based on binding affinity, molecular properties, drug-likeness, toxicity parameters, ligand interactions, bioavailability, synthetic accessibility, structure–activity relationship, and comparative analysis of our experimental findings with other studies, C_5 was identified as the most promising phytocompound. C_5 interacted with the active site residues of SARS-CoV-2 Mpro (GLU166, ARG188, GLN189) and furin (ASN295, ARG298, HIS364, THR365). Many phytocompounds that interacted with these amino acid residues were reported by other studies as potential inhibitors of SARS-CoV-2 Mpro and furin. The oxygen atom at position 18, the –OH group at position 19, and the 6-C-glucoside were identified as the pharmacophores in isovitexin (also known as apigenin-6-C-glucoside). Other in-silico studies reported apigenin as a potential inhibitor of SARS-CoV-2 Mpro and apigenin-o-7-glucuronide was reported to show stable conformation during MD simulations with SARS-CoV-2 Mpro. Conclusion: The present study found isovitexin as the most promising phytocompound to potentially inhibit the cellular entry and viral replication of SARS-CoV-2. We also conclude that compounds having oxygen atom at position 18 (C-ring), –OH group at position 19 (A-ring), and 6-C-glucoside attached to the A-ring at position 3 on a C6– C3–C6 Fri, 01 Jan 2021 00:00:00 GMT http://pucir.inflibnet.ac.in:8080/jspui/handle/123456789/909 2021-01-01T00:00:00Z http://pucir.inflibnet.ac.in:8080/jspui/handle/123456789/908 Title: Global data on earthworm abundance, biomass, diversity and corresponding environmental properties Authors: Lalthanzara, H Abstract: Earthworms are an important soil taxon as ecosystem engineers, providing a variety of crucial ecosystem functions and services. Little is known about their diversity and distribution at large spatial scales, despite the availability of considerable amounts of local-scale data. Earthworm diversity data, obtained from the primary literature or provided directly by authors, were collated with information on site locations, including coordinates, habitat cover, and soil properties. Datasets were required, at a minimum, to include abundance or biomass of earthworms at a site. Where possible, site-level species lists were included, as well as the abundance and biomass of individual species and ecological groups. This global dataset contains 10,840 sites, with 184 species, from 60 countries and all continents except Antarctica. The data were obtained from 182 published articles, published between 1973 and 2017, and 17 unpublished datasets. Amalgamating data into a single global database will assist researchers in investigating and answering a wide variety of pressing questions, for example, jointly assessing aboveground and belowground biodiversity distributions and drivers of biodiversity change. Fri, 01 Jan 2021 00:00:00 GMT http://pucir.inflibnet.ac.in:8080/jspui/handle/123456789/908 2021-01-01T00:00:00Z